High proportion of PD-1 and CD39 positive CD8+ tissue resident T lymphocytes correlates with better clinical outcome in resected human oesophageal adenocarcinoma

Objective: To understand the CD8+ tumour infiltrating lymphocyte (TIL) compartment of oesophageal adenocarcinoma (OAC) with regards to markers of lymphocyte exhaustion, tissue residency and to identify possible reasons behind differential responses to therapy. Design: Tumour samples from 44 patients...

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Detalhes bibliográficos
Principais autores: Hill, SL, Sugiyarto, G, Harrington, J, James, E, Underwood, TJ, Elliott, T
Formato: Journal article
Idioma:English
Publicado em: Springer 2024