Diversity in cortical thymic epithelial cells occurs through loss of a Foxn1-dependent gene signature driven by stage-specific thymocyte cross-talk

<p>In the thymus, cortical thymic epithelial cells (cTECs) and medullary thymic epithelial cells support &alpha;&beta;T cell development from lymphoid progenitors. For cTECs, expression of a specialized gene signature that includes&nbsp;<em>Cxcl12</em>,&nbsp;<em&...

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Bibliographic Details
Main Authors: White, AJ, Parnell, SM, Handel, A, Maio, S, Bacon, A, Cosway, EJ, Lucas, B, James, KD, Cowan, JE, Jenkinson, WE, Hollander, GA, Anderson, G
Format: Journal article
Language:English
Published: American Association of Immunologists 2023