The effects of a partitioned var gene repertoire of Plasmodium falciparum on antigenic diversity and the acquisition of clinical immunity.
BACKGROUND: The human malaria parasite Plasmodium falciparum exploits antigenic diversity and within-host antigenic variation to evade the host's immune system. Of particular importance are the highly polymorphic var genes that encode the family of cell surface antigens PfEMP1 (Plasmodium falc...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
BioMed Central
2008
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