An unusual eukaryotic protein phosphatase required for transcription by RNA polymerase II and CTD dephosphorylation in S. cerevisiae.

The carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II is phosphorylated soon after transcriptional initiation. We show here that the essential FCP1 gene of S. cerevisiae is linked genetically to RNA polymerase II and encodes a CTD phosphatase essential for dephosphorylation o...

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Bibliographic Details
Main Authors: Kobor, MS, Archambault, J, Lester, W, Holstege, F, Gileadi, O, Jansma, D, Jennings, E, Kouyoumdjian, F, Davidson, A, Young, R, Greenblatt, J
Format: Journal article
Language:English
Published: 1999