The impact of genetic polymorphisms on the pharmacokinetics of efavirenz in African children
<h4>Aim</h4> <p>To characterise the efavirenz steady-state pharmacokinetics in African children using model-based approach, quantifying demographic and genotypic effects on the drug’s disposition, and conduct simulations allowing prediction of optimised doses of efavirenz in this p...
| Main Authors: | , , , , , , , , , , , , |
|---|---|
| Format: | Journal article |
| Published: |
Wiley
2016
|