The impact of genetic polymorphisms on the pharmacokinetics of efavirenz in African children

The impact of genetic polymorphisms on the pharmacokinetics of efavirenz in African children

<h4>Aim</h4> <p>To characterise the efavirenz steady-state pharmacokinetics in African children using model-based approach, quantifying demographic and genotypic effects on the drug’s disposition, and conduct simulations allowing prediction of optimised doses of efavirenz in this p...

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Main Authors: Bienczak, A, Cook, A, Wiesner, L, Olagunju, A, Mulenga, V, Kityo, C, Kekitiinwa, A, Owen, A, Walker, A, Gibb, D, McIlleron, H, Burger, D, Denti, P
Format: Journal article
Published: Wiley 2016

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