A highly enantioselective total synthesis of (+)-goniodiol.
A high-yielding enantioselective total synthesis of the bioactive styryllactone (+)-goniodiol has been realised, starting from readily available (S)-glycidol. A key step is an oxygen-to-carbon rearrangement of a silyl enol ether linked via an anomeric centre, facilitating the rapid and diastereosele...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2006
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