Modulating Anti-MicroRNA-21 Activity and Specificity Using Oligonucleotide Derivatives and Length Optimization.

MicroRNAs are short, endogenous RNAs that direct posttranscriptional regulation of gene expression vital for many developmental and cellular functions. Implicated in the pathogenesis of several human diseases, this group of RNAs provides interesting targets for therapeutic intervention. Anti-microRN...

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Bibliographic Details
Main Authors: Muñoz-Alarcón, A, Guterstam, P, Romero, C, Behlke, M, Lennox, K, Wengel, J, Andaloussi, S, Langel, U
Format: Journal article
Language:English
Published: 2012