Vaccination with Plasmodium vivax Duffy-binding protein inhibits parasite growth during controlled human malaria infection

There are no licensed vaccines against Plasmodium vivax. We conducted two Phase I/IIa clinical trials to assess two vaccines targeting P. vivax Duffy-binding protein region II (PvDBPII). Recombinant viral vaccines using chimpanzee adenovirus 63 (ChAd63) and modified vaccinia virus Ankara (MVA) vecto...

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Main Authors:	Hou, M, Barrett, JR, Themistocleous, Y, Rawlinson, TA, Diouf, A, Martinez, FJ, Nielsen, CM, Lias, AM, King, LDW, Edwards, NJ, Greenwood, NM, Kingham, L, Poulton, I, Khozoee, B, Goh, C, Hodgson, SH, Mac lochlainn, D, Salkeld, J, Guillotte-Blisnick, M, Huon, C, Mohring, F, Reimer, JM, Chauhan, VS, Biswas, S, Lawrie, AM, Silk, SE, Minassian, AM, Draper, SJ, Mukherjee, P, Taylor, IJ, Cho, J, Nugent, FL, Long, CA, Moon, RW, Miura, K, Chitnis, CE
Format:	Journal article
Language:	English
Published:	American Association for the Advancement of Science 2023

Vaccination with Plasmodium vivax Duffy-binding protein inhibits parasite growth during controlled human malaria infection

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