Low affinity antibodies against collagen type II are associated with pathology in collagen-induced arthritis in mice.

The relationship between the functional affinity of antibodies against type II collagen (CII) and the development of arthritis was studied in mice with collagen-induced arthritis. The responses of DBA/1 strain mice were compared with those of mice selectively bred to produce antibodies of high funct...

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Bibliographic Details
Main Authors: Staines, N, Ekong, T, Thompson, H, Isaacs, AB, Loryman, B, Major, P, Hobbs, S, Devey, M
Format: Journal article
Language:English
Published: 1990