Random intermittent search and the tug-of-war model of motor-driven transport

We formulate the tug-of-war model of microtubule cargo transport by multiple molecular motors as an intermittent random search for a hidden target. A motor-complex consisting of multiple molecular motors with opposing directional preference is modeled using a discrete Markov process. The motors rand...

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Bibliographic Details
Main Authors: Newby, J, Bressloff, P
Format: Journal article
Published: 2010