Simultaneous inhibition of LSD1 and TGFβ enables eradication of poorly immunogenic tumors with Anti-PD-1 treatment
Epigenetic regulators are a class of promising targets in combination with immune checkpoint inhibitors for cancer treatment, but the impact of the broad effects of perturbing epigenetic regulators on tumor immunotherapy remains to be fully explored. Here we show that ablation of the histone demethy...
| Main Authors: | , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
American Association for Cancer Research
2021
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