The trypanosome transcriptome is remodelled during differentiation but displays limited responsiveness within life stages.

BACKGROUND: Trypanosomatids utilise polycistronic transcription for production of the vast majority of protein-coding mRNAs, which operates in the absence of gene-specific promoters. Resolution of nascent transcripts by polyadenylation and trans-splicing, together with specific rates of mRNA turnov...

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Bibliographic Details
Main Authors: Koumandou, V, Natesan, S, Sergeenko, T, Field, M
Format: Journal article
Language:English
Published: BioMed Central 2008