Composition and antigenic effects of individual glycan sites of a trimeric HIV-1 envelope glycoprotein

The HIV-1 envelope glycoprotein trimer is covered by an array of N-linked glycans that shield it from immune surveillance. The high density of glycans on the trimer surface imposes steric constraints limiting the actions of glycan processing enzymes, such that multiple under-processed structures rem...

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Bibliographic Details
Main Authors:	Crispin, M, Behrens, A, Vasiljevic, S, Pritchard, L, Harvey, D, Andev, R, Krumm, S, Struwe, W, Cupo, A, Kumar, A, Zitzmann, N, Seabright, G, Kramer, H, Spencer, D, Royle, L, Lee, J, Klasse, P, Burton, D, Wilson, I, Ward, A, Sanders, R, Moore, J, Doores, K
Format:	Journal article
Published:	Cell Press 2016

Composition and antigenic effects of individual glycan sites of a trimeric HIV-1 envelope glycoprotein

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