Biallelic TLR4 deficiency in humans

<p><strong>Background</strong><br> Toll-like receptors (TLRs) mediate functions for host defense and inflammatory responses. TLR4 recognizes LPS, a component of gram-negative bacteria as well as host-derived endogenous ligands such as S100A8 and S100A9 proteins.<br><...

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Bibliographic Details
Main Authors: Capitani, M, Al-Shaibi, AA, Pandey, S, Gartner, L, Taylor, H, Hubrack, SZ, Agrebi, N, Al-Mohannadi, MJ, Al Kaabi, S, Vogl, T, Roth, J, Kotlarz, D, Klein, C, Charles, AK, Vijayakumar, V, Karim, MY, George, B, Travis, SP, Elawad, M, Lo, B, Uhlig, HH
Format: Journal article
Language:English
Published: Elsevier 2022