Production, crystallization, and preliminary X-ray analysis of the human MHC class Ib molecule HLA-E.

HLA-E is the first human class Ib major histocompatibility complex molecule to be crystallized. HLA-E is highly conserved and almost nonpolymorphic, and has recently been shown to be the first specialized ligand for natural killer cell receptors. In functional studies, HLA-E is unlike the class Ia M...

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Bibliographic Details
Main Authors: O'Callaghan, C, Tormo, J, Willcox, B, Blundell, C, Jakobsen, B, Stuart, D, Mcmichael, A, Bell, J, Jones, E
Format: Journal article
Language:English
Published: 1998