PIM kinases are progression markers and emerging therapeutic targets in diffuse large B-cell lymphoma.

BACKGROUND: PIM serine/threonine kinases are often highly expressed in haematological malignancies. We have shown that PIM inhibitors reduced the survival and migration of leukaemic cells. Here, we investigated PIM kinases in diffuse large B-cell lymphoma (DLBCL) biopsy samples and DLBCL cell lines....

Full description

Bibliographic Details
Main Authors: Brault, L, Menter, T, Obermann, E, Knapp, S, Thommen, S, Schwaller, J, Tzankov, A
Format: Journal article
Language:English
Published: 2012