Genetic screening to investigate treatment resistance in MLL-rearranged leukemia
<p>Despite the promise of targeted cancer therapies, some subsets of acute myeloid leukemia (AML) and acute lymphoid leukemia (ALL) continue to present a dismal prognosis. Translocations in the mixed lineage leukemia (MLL) gene generate MLL fusion proteins and cause MLL-rearranged (MLLr) leuke...
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| Format: | Thesis |
| Language: | English |
| Published: |
2019
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