Genetic screening to investigate treatment resistance in MLL-rearranged leukemia
<p>Despite the promise of targeted cancer therapies, some subsets of acute myeloid leukemia (AML) and acute lymphoid leukemia (ALL) continue to present a dismal prognosis. Translocations in the mixed lineage leukemia (MLL) gene generate MLL fusion proteins and cause MLL-rearranged (MLLr) leuke...
Prif Awdur: | Jamilly, M |
---|---|
Awduron Eraill: | Milne, TA |
Fformat: | Traethawd Ymchwil |
Iaith: | English |
Cyhoeddwyd: |
2019
|
Pynciau: |
Eitemau Tebyg
-
TET1 plays an essential oncogenic role in MLL-rearranged leukemia
gan: Jaenisch, Rudolf, et al.
Cyhoeddwyd: (2014) -
Potent, p53-independent induction of NOXA sensitizes MLL-rearranged B-cell acute lymphoblastic leukemia cells to venetoclax
gan: Fidyt, K, et al.
Cyhoeddwyd: (2022) -
The role of RAS mutations in MLL-rearranged leukaemia: a path to intervention?
gan: Mansur, MB, et al.
Cyhoeddwyd: (2017) -
Screening and characterization of antimalarial resistance related genetic structural variations in P. falciparum
gan: Assisi, Christina
Cyhoeddwyd: (2022) -
Extending the repertoire of the mixed-lineage leukemia gene MLL in leukemogenesis.
gan: Daser, A, et al.
Cyhoeddwyd: (2004)