PET imaging of PARP expression using [18F]olaparib

PARP inhibitors are increasingly being studied as cancer drugs, as single agents or as a part of combination therapies. Imaging of PARP using a radiolabeled inhibitor has been proposed for patient selection, outcome prediction, dose optimization, genotoxic therapy evaluation, and target engagement i...

Повний опис

Бібліографічні деталі
Автори: Wilson, T, Xavier, M, Knight, J, Verhoog, S, Torres, J, Mosley, M, Hopkins, S, Wallington, S, Allen, P, Kersemans, V, Hueting, R, Smart, S, Gouverneur, V, Cornelissen, B
Формат: Journal article
Опубліковано: Society of Nuclear Medicine 2018