Exploitation of sub-micron cavitation nuclei to enhance ultrasound-mediated transdermal transport and penetration of vaccines

Inertial cavitation mediated by ultrasound has been previously shown to enable skin permeabilisation for transdermal drug and vaccine delivery, by sequentially applying the ultrasound then the therapeutic in liquid form on the skin surface. Using a novel hydrogel dosage form, we demonstrate that the...

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Bibliographic Details
Main Authors: Bhatnagar, S, Kwan, J, Shah, A, Coussios, C, Carlisle, R
Format: Journal article
Language:English
Published: Elsevier 2016