Divergent functions and distinct localization of the Notch ligands DLL1 and DLL3 in vivo
The Notch ligands Dll1 and Dll3 are coexpressed in the presomitic mesoderm of mouse embryos. Despite their coexpression, mutations in Dll1 and Dll3 cause strikingly different defects. To determine if there is any functional equivalence, we replaced Dll1 with Dll3 in mice. Dll3 does not compensate fo...
| Main Authors: | , , , , , , , , , , |
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| Format: | Journal article |
| Published: |
Rockefeller University Press
2007
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