Avathrin: a novel thrombin inhibitor derived from a multi-copy precursor in the salivary glands of the ixodid tick, Amblyomma variegatum

Tick saliva is a rich source of antihemostatic compounds. We amplified a cDNA from the salivary glands of the tropical bont tick (Amblyomma variegatum) using primers based on the variegin sequence, which we previously identified as a novel thrombin inhibitor from the same tick species. The transcrip...

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Bibliographic Details
Main Authors: Iyer, J, Koh, C, Kazimirova, M, Roller, L, Jobichen, C, Swaminathan, K, Mizuguchi, J, Iwanaga, S, Nuttall, P, Chan, M, Kini, R
Format: Journal article
Published: Federation of American Society of Experimental Biology 2017