Base-flipping dynamics in a DNA hairpin processing reaction

Many enzymes that repair or modify bases in double-stranded DNA gain access to their substrates by base flipping. Although crystal structures provide stunning snap shots, biochemical approaches addressing the dynamics have proven difficult, particularly in complicated multi-step reactions. Here, we...

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Bibliographic Details
Main Authors: Bischerour, J, Chalmers, R
Format: Journal article
Language:English
Published: Oxford University Press 2007
Subjects: