Comparative genome analysis delimits a chromosomal domain and identifies key regulatory elements in the alpha globin cluster.

We have cloned, sequenced and annotated segments of DNA spanning the mouse, chicken and pufferfish alpha globin gene clusters and compared them with the corresponding region in man. This has defined a small segment ( approximately 135-155 kb) of synteny and conserved gene order, which may contain al...

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Bibliographic Details
Main Authors: Flint, J, Tufarelli, C, Peden, J, Clark, K, Daniels, R, Hardison, R, Miller, W, Philipsen, S, Tan-Un, K, McMorrow, T, Frampton, J, Alter, B, Frischauf, A, Higgs, D
Format: Journal article
Language:English
Published: 2001