Replication by the Epistasis Project of the interaction between the genes for IL-6 and IL-10 in the risk of Alzheimer's disease.

BACKGROUND: Chronic inflammation is a characteristic of Alzheimer's disease (AD). An interaction associated with the risk of AD has been reported between polymorphisms in the regulatory regions of the genes for the pro-inflammatory cytokine, interleukin-6 (IL-6, gene: IL6), and the anti-inflam...

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Main Authors: Combarros, O, van Duijn, C, Hammond, N, Belbin, O, Arias-Vásquez, A, Cortina-Borja, M, Lehmann, MG, Aulchenko, Y, Schuur, M, Kölsch, H, Heun, R, Wilcock, G, Brown, K, Kehoe, P, Harrison, R, Coto, E, Alvarez, V, Deloukas, P, Mateo, I, Gwilliam, R, Morgan, K, Warden, DR, Smith, A, Lehmann, D
Format: Journal article
Language:English
Published: 2009