Mapping of the region of complement receptor (CR) 1 required for Plasmodium falciparum rosetting and demonstration of the importance of CR1 in rosetting in field isolates.

The malaria parasite Plasmodium falciparum induces a number of novel adhesion properties in the erythrocytes that it infects. One of these properties, the ability of infected erythrocytes to bind uninfected erythrocytes to form rosettes, is associated with severe malaria and may play a direct role i...

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Detalhes bibliográficos
Principais autores: Rowe, J, Rogerson, S, Raza, A, Moulds, J, Kazatchkine, MD, Marsh, K, Newbold, C, Atkinson, J, Miller, L
Formato: Journal article
Idioma:English
Publicado em: 2000