ATP hydrolysis is required for relocating cohesin from sites occupied by its Scc2/4 loading complex

Background: The Cohesin complex that holds sister chromatins together until anaphase is comprised of three core subunits: Smc1 and Smc3, two long-rod-shaped proteins with an ABC-like ATPase head (nucleotide-binding domain [NBD]) and a dimerization domain linked by a 50 nm long intramolecular antipar...

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Bibliographic Details
Main Authors: Hu, B, Itoh, T, Mishra, A, Katoh, Y, Chan, K, Upcher, W, Godlee, C, Roig, M, Shirahige, K, Nasmyth, K
Format: Journal article
Language:English
Published: 2011