A mathematical model of the murine ventricular myocyte: a data-driven biophysically based approach applied to mice overexpressing the canine NCX isoform.

Mathematical modeling of Ca(2+) dynamics in the heart has the potential to provide an integrated understanding of Ca(2+)-handling mechanisms. However, many previous published models used heterogeneous experimental data sources from a variety of animals and temperatures to characterize model paramete...

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Bibliographic Details
Main Authors: Li, L, Niederer, SA, Idigo, W, Zhang, Y, Swietach, P, Casadei, B, Smith, N
Format: Journal article
Language:English
Published: 2010