The effect of anti-alpha4 integrin antibody on brain lesion activity in MS. The UK Antegren Study Group.

OBJECTIVE: To determine the effect of humanized monoclonal antibody against alpha4 integrin (reactive with alpha4beta1 integrin or very-late antigen-4) on MRI lesion activity in MS. METHODS: A randomized, double-blind, placebo-controlled trial in 72 patients with active relapsing-remitting and secon...

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Bibliographic Details
Main Authors: Tubridy, N, Behan, P, Capildeo, R, Chaudhuri, A, Forbes, R, Hawkins, C, Hughes, R, Palace, J, Sharrack, B, Swingler, R, Young, C, Moseley, I, MacManus, D, Donoghue, S, Miller, D
Format: Journal article
Language:English
Published: 1999