Accessibility to peptidoglycan is important for the recognition of gram-positive bacteria in drosophila

In Drosophila, it is thought that peptidoglycan recognition proteins (PGRPs) SA and LC structurally discriminate between bacterial peptidoglycans with lysine (Lys) or diaminopimelic (DAP) acid, respectively, thus inducing differential antimicrobial transcription response. Here, we find that accessib...

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Bibliographic Details
Main Authors: Vaz, F, Kounatidis, I, Covas, G, Parton, R, Harkiolaki, M, Davis, I, Filipe, S, Ligoxygakis, P
Format: Journal article
Published: Cell Press 2019