Fitness cost of escape mutations in p24 Gag in association with control of human immunodeficiency virus type 1.

Mutational escape by human immunodeficiency virus (HIV) from cytotoxic T-lymphocyte (CTL) recognition is a major challenge for vaccine design. However, recent studies suggest that CTL escape may carry a sufficient cost to viral replicative capacity to facilitate subsequent immune control of a now at...

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Những tác giả chính: Martinez-Picado, J, Prado, J, Fry, E, Pfafferott, K, Leslie, A, Chetty, S, Thobakgale, C, Honeyborne, I, Crawford, H, Matthews, P, Pillay, T, Rousseau, C, Mullins, J, Brander, C, Walker, B, Stuart, D, Kiepiela, P, Goulder, P
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 2006