Pneumococcal conjugate vaccine induced IgG and nasopharyngeal carriage of pneumococci: Hyporesponsiveness and immune correlates of protection for carriage

Background Prior studies have demonstrated hyporesponsiveness to pneumococcal conjugate vaccines (PCVs) when administered in the presence of homologous carriage. This may be substantially more important in Africa where carriage prevalence is high. Deriving a correlate of protection (CoP) for carriag...

Full description

Bibliographic Details
Main Authors: Ojal, J, Hammitt, L, Gaitho, J, Scott, J, Goldblatt, D
Format: Journal article
Published: Elsevier 2017