Variation in the ICAM1 gene is not associated with severe malaria phenotypes.
Evidence from autopsy and in vitro binding studies suggests that adhesion of erythrocytes infected with Plasmodium falciparum to the human host intercellular adhesion molecule (ICAM)-1 receptor is important in the pathogenesis of severe malaria. Previous association studies between polymorphisms in...
Main Authors: | Fry, A, Auburn, S, Diakite, M, Green, A, Richardson, A, Wilson, J, Jallow, M, Sisay-Joof, F, Pinder, M, Griffiths, M, Peshu, N, Williams, T, Marsh, K, Molyneux, M, Taylor, T, Rockett, K, Kwiatkowski, D |
---|---|
Format: | Journal article |
Sprog: | English |
Udgivet: |
2008
|
Lignende værker
-
Common variation in the ABO glycosyltransferase is associated with susceptibility to severe Plasmodium falciparum malaria.
af: Fry, A, et al.
Udgivet: (2008) -
Further evidence supporting a role for gs signal transduction in severe malaria pathogenesis
af: Auburn, S, et al.
Udgivet: (2010) -
Tumor necrosis factor and lymphotoxin-alpha polymorphisms and severe malaria in African populations.
af: Clark, T, et al.
Udgivet: (2009) -
Association of the GNAS locus with severe malaria.
af: Auburn, S, et al.
Udgivet: (2008) -
Lack of association of interferon regulatory factor 1 with severe malaria in affected child-parental trio studies across three African populations
af: Mangano, V, et al.
Udgivet: (2009)