Plasma biomarkers of HIV-related systemic inflammation and immune activation in sub-Saharan Africa before and during suppressive antiretroviral therapy

We evaluated immune biomarker profiles in HIV-infected adults (n=398) from 5 African countries. Although all biomarkers decreased after ART initiation, CXCL10, LBP, CRP, sCD163 and sCD14 were significantly higher during ART than in an HIV-negative reference group (n=90), indicating persistent monocy...

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Bibliographic Details
Main Authors: Kroeze, S, Wit, F, Rossouw, T, Steel, H, Kityo, C, Siwale, M, Akanmu, S, Mandaliya, K, De Jager, M, Ondoa, P, Reiss, P, Rinke De Wit, T, Kootstra, N, Hamers, R
Format: Journal article
Language:English
Published: Oxford University Press 2019