Detection of somatic changes in human cancer DNA by DNA fingerprint analysis.

Minisatellite DNA probes which can detect a large number of autosomal loci dispersed throughout the human genome were used to examine the constitutional and tumour DNA of 35 patients with a variety of cancers of which eight were of gastrointestinal origin. Somatic changes were seen in the tumour DNA...

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Bibliographic Details
Main Authors: Thein, S, Jeffreys, A, Gooi, H, Cotter, F, Flint, J, O'Connor, N, Weatherall, D, Wainscoat, J
Format: Journal article
Language:English
Published: 1987