Detection of somatic changes in human cancer DNA by DNA fingerprint analysis.
Minisatellite DNA probes which can detect a large number of autosomal loci dispersed throughout the human genome were used to examine the constitutional and tumour DNA of 35 patients with a variety of cancers of which eight were of gastrointestinal origin. Somatic changes were seen in the tumour DNA...
Main Authors: | Thein, S, Jeffreys, A, Gooi, H, Cotter, F, Flint, J, O'Connor, N, Weatherall, D, Wainscoat, J |
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Format: | Journal article |
Language: | English |
Published: |
1987
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