The function of PRC2 in MLL-AF4 acute lymphoid leukaemia
<p>The MLL-AF4 fusion protein is the most prevalent MLL rearrangement in acute lymphoid leukaemia. It is associated with a very poor prognosis with median overall survival of 10 months in children. Epigenetic therapy is a promising new approach for the treatment haematological malignancies. P...
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2015
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