Playing the end game: DNA double-strand break repair pathway choice.
DNA double-strand breaks (DSBs) are highly toxic lesions that can drive genetic instability. To preserve genome integrity, organisms have evolved several DSB repair mechanisms, of which nonhomologous end-joining (NHEJ) and homologous recombination (HR) represent the two most prominent. It has recent...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2012
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