The forgotten APOE allele: A review of the evidence and suggested mechanisms for the protective effect of APOE e2

The forgotten APOE allele: A review of the evidence and suggested mechanisms for the protective effect of APOE e2

Ongoing efforts to improve survival, and enhance quality of life have led biomedical research to focus on disease and the mechanisms that increase risk for disease. The other side of that coin may be as important, i.e. examining the protective factors that allow some individuals to enjoy long, healt...

Volledige beschrijving

Bibliografische gegevens
Hoofdauteurs:	Suri, S, Heise, V, Trachtenberg, A, Mackay, C
Formaat:	Journal article
Taal:	English
Gepubliceerd in:	2013

Gelijkaardige items

The forgotten APOE allele: a review of the evidence and suggested mechanisms for the protective effect of APOE ɛ2.
door: Suri, S, et al.
Gepubliceerd in: (2013)

The APOE ɛ4 allele modulates brain white matter integrity in healthy adults.
door: Heise, V, et al.
Gepubliceerd in: (2011)

The APOE 4 allele modulates brain white matter integrity in healthy adults
door: Heise, V, et al.
Gepubliceerd in: (2011)

The effects of APOE-ε4 on the BOLD response
door: Trachtenberg, A, et al.
Gepubliceerd in: (2010)

The effects of APOE-ε4 on the BOLD response.
door: Trachtenberg, A, et al.
Gepubliceerd in: (2012)

Protective effect of the APOE-e3 allele in Alzheimer’s disease
door: B.V.P. de-Almada, et al.
Gepubliceerd in: (2012-01-01)

Reduced cerebrovascular reactivity in young adults carrying the APOE ε4 allele.
door: Suri, S, et al.
Gepubliceerd in: (2015)

Protective effect of the APOE-e3 allele in Alzheimer’s disease
door: B.V.P. de-Almada, et al.
Gepubliceerd in: (2012-01-01)

The effects of APOE on the functional architecture of the resting brain
door: Trachtenberg, A, et al.
Gepubliceerd in: (2011)

The effects of APOE on the functional architecture of the resting brain.
door: Trachtenberg, A, et al.
Gepubliceerd in: (2012)

Genetic risk and resilience for Alzheimer’s disease: The effect of the three APOE alleles on brain function across life
door: Suri, S
Gepubliceerd in: (2016)

Murine Gut Microbiome Association With APOE Alleles
door: Ishita J. Parikh, et al.
Gepubliceerd in: (2020-02-01)

ApoE genotype affects allele-specific apo[a] levels for large apo[a] sizes in African Americans: the Harlem-Basset Studys⃞
door: Erdembileg Anuurad, et al.
Gepubliceerd in: (2007-03-01)

Distinct patterns of brain activity in young carriers of the APOE-epsilon4 allele.
door: Filippini, N, et al.
Gepubliceerd in: (2009)

APOE GENE POLYMORPHISM: THE IMPACT OF APOE4 ALLELE ON SYSTEMIC INFLAMMATION AND ITS ROLE IN THE PATHOGENESIS OF ALZHEIMER’S DISEASE
door: I. K. Malashenkova, et al.
Gepubliceerd in: (2018-06-01)

Apo[a] size and PNR explain African American-Caucasian differences in allele-specific apo[a] levels for small but not large apo[a]
door: Jill Rubin, et al.
Gepubliceerd in: (2006-05-01)

Targeted In Situ Gene Correction of Dysfunctional APOE Alleles to Produce Atheroprotective Plasma ApoE3 Protein
door: Ioannis Papaioannou, et al.
Gepubliceerd in: (2012-01-01)

Hepatic secretion of apoB-100 is impaired in hypobetalipoproteinemic mice with an apoB-38.9-specifying allele
door: Zhouji Chen, et al.
Gepubliceerd in: (2004-01-01)

APOE2: protective mechanism and therapeutic implications for Alzheimer’s disease
door: Zonghua Li, et al.
Gepubliceerd in: (2020-11-01)

Differential effects of the APOE genotype on brain function across the lifespan.
door: Filippini, N, et al.
Gepubliceerd in: (2011)

Differential effects of the APOE genotype on brain function across the lifespan
door: Filippini, N, et al.
Gepubliceerd in: (2010)

The effects of APOE on brain activity do not simply reflect the risk of Alzheimer's disease
door: Trachtenberg, A, et al.
Gepubliceerd in: (2012)

The effects of APOE on brain activity do not simply reflect the risk of Alzheimer's disease.
door: Trachtenberg, A, et al.
Gepubliceerd in: (2012)

A comprehensive analysis of APOE genotype effects on human brain structure in the UK Biobank
door: Heise, V, et al.
Gepubliceerd in: (2024)

Evidence for differential effects of apoE3 and apoE4 on HDL metabolism
door: Paul C.R. Hopkins, et al.
Gepubliceerd in: (2002-11-01)

Association of the APOE epsilon4 allele with disease activity in multiple sclerosis.
door: Evangelou, N, et al.
Gepubliceerd in: (1999)

Effect of APOE ε4 allele on survival and fertility in an adverse environment.
door: Eric van Exel, et al.
Gepubliceerd in: (2017-01-01)

MRI Markers of Small Vessel Disease and the APOE Allele in Cognitive Impairment
door: Mana Shams, et al.
Gepubliceerd in: (2022-07-01)

A TOMM40/APOE allele encoding APOE‐E3 predicts high likelihood of late‐onset Alzheimer’s disease in autopsy cases
door: Selma M. Soyal, et al.
Gepubliceerd in: (2020-08-01)

A CHRONOLOGY OF CUBA'S 'UPDATING OF THE SOCIALIST MODEL'
door: Philip Peters
Gepubliceerd in: (2012-09-01)

Sex differences in gene expression patterns associated with the APOE4 allele [version 2; peer review: 2 approved]
door: Michelle Hsu, et al.
Gepubliceerd in: (2019-07-01)

Worldwide Distribution of Apolipoprotein E Gene Alleles: is APOE*e4 Allele a Factor of Adaptation to Climate in Humans?
door: F Ghasemian Rodsari, et al.
Gepubliceerd in: (2005-03-01)

Worldwide Distribution of Apolipoprotein E Gene Alleles: is APOE*e4 Allele a Factor of Adaptation to Climate in Humans?
door: F Ghasemian Rodsari, et al.
Gepubliceerd in: (2005-10-01)

Characteristics of coupled unstable modes in a Supersonic ''Top-hat'' Round Jet
door: Daisuke WATANABE
Gepubliceerd in: (2024-02-01)

Reduced physiological complexity in robust elderly adults with the APOE epsilon4 allele.
door: Daniel Cheng, et al.
Gepubliceerd in: (2009-11-01)

A comprehensive analysis of APOE genotype effects on human brain structure in the UK Biobank
door: Verena Heise, et al.
Gepubliceerd in: (2024-03-01)

Plasma turnover of HDL apoC-I, apoC-III, and apoE in humans
door: Jeffrey S. Cohn, et al.
Gepubliceerd in: (2003-10-01)

(Z)-N-(7-Cyano-9,9,15,15-tetramethyl-9,10,11,13,14,15-hexahydro-6H-benzo[4&apos;&apos;,5&apos;&apos;]imidazo[1&apos;&apos;,2&apos;&apos;:1&apos;,2&apos;]pyrido[3&apos;,4&apos;:5, 6]pyrano[2,3-f]pyrido[3,2,1-ij]quinolin-6-ylidene)pent-4-ynamide
door: David D. Díaz, et al.
Gepubliceerd in: (2012-10-01)

Cardiovascular Protection by ApoE and ApoE-HDL Linked to Suppression of ECM Gene Expression and Arterial Stiffening
door: Devashish Kothapalli, et al.
Gepubliceerd in: (2012-11-01)

Generation of three isogenic, gene-edited iPSC lines carrying the APOE-Christchurch mutation into the three common APOE variants: APOE2Ch, APOE3Ch and APOE4Ch
door: Mansour Haidar, et al.
Gepubliceerd in: (2024-06-01)