Double-blind randomized controlled clinical trial of the interleukin-6 receptor antagonist, tocilizumab, in European patients with rheumatoid arthritis who had an incomplete response to methotrexate.

OBJECTIVE: To establish the safety and efficacy of repeat infusions of tocilizumab (previously known as MRA), a humanized anti-interleukin-6 (IL-6) receptor antibody, alone and in combination with methotrexate (MTX), for the treatment of rheumatoid arthritis (RA). METHODS: The study group comprised...

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Bibliographic Details
Main Authors: Maini, R, Taylor, P, Szechinski, J, Pavelka, K, Bröll, J, Balint, G, Emery, P, Raemen, F, Petersen, J, Smolen, J, Thomson, D, Kishimoto, T
Format: Journal article
Language:English
Published: 2006