A Refined Open State of the Glycine Receptor Obtained via Molecular Dynamics Simulations

Pentameric ligand-gated ion channels are key players in mediating fast neurotransmission. Glycine receptors are chloride-selective members of this receptor family that mediate inhibitory synaptic transmission and are implicated in neurological disorders including autism and hyperekplexia. They have...

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Bibliographic Details
Main Authors: Dämgen, MA, Biggin, PC
Format: Journal article
Language:English
Published: Cell Press 2019