HLA-DR is aberrantly expressed at feto-maternal interface in pre-eclampsia

In normal pregnancy, villous cytotrophoblast and syncytiotrophoblast do not express HLA Class I and Class II molecules, while invasive extravillous trophoblast only express class I HLA-C and the atypical class Ib antigens, HLA-G, -E and -F. Inadequate maternal tolerance of invasive trophoblast has b...

Full description

Bibliographic Details
Main Authors: Tersigni, C, Redman, C, Dragovic, R, Tannetta, D, Scambia, G, Di Simone, N, Sargent, I, Vatish, M
Format: Journal article
Language:English
Published: Elsevier 2018