R-loop immunoprecipitation: a method to detect R-loop interacting factors
R-loops are non-B-DNA structures consisting of an RNA/DNA hybrid and a displaced single-stranded DNA. They arise during transcription and play important biological roles. However, perturbation of R-loop levels represents a source of DNA damage and genome instability resulting in human diseases, incl...
Autori principali: | , |
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Natura: | Book section |
Lingua: | English |
Pubblicazione: |
Springer
2022
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