R-loop immunoprecipitation: a method to detect R-loop interacting factors

R-loops are non-B-DNA structures consisting of an RNA/DNA hybrid and a displaced single-stranded DNA. They arise during transcription and play important biological roles. However, perturbation of R-loop levels represents a source of DNA damage and genome instability resulting in human diseases, incl...

Повний опис

Бібліографічні деталі
Автори: Beghè, C, Gromak, N
Формат: Book section
Мова:English
Опубліковано: Springer 2022