Variant ABO blood group alleles, secretor status, and risk of pancreatic cancer: results from the pancreatic cancer cohort consortium.

BACKGROUND: Subjects with non-O ABO blood group alleles have increased risk of pancreatic cancer. Glycosyltransferase activity is greater for the A(1) versus A(2) variant, whereas O01 and O02 variants are nonfunctioning. We hypothesized: 1) A(1) allele would confer greater risk than A(2) allele, 2)...

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Bibliographic Details
Main Authors: Wolpin, B, Kraft, P, Xu, M, Steplowski, E, Olsson, M, Arslan, A, Bueno-de-Mesquita, H, Gross, M, Helzlsouer, K, Jacobs, E, LaCroix, A, Petersen, G, Stolzenberg-Solomon, R, Zheng, W, Albanes, D, Allen, N, Amundadottir, L, Austin, M, Boutron-Ruault, M, Buring, J, Canzian, F, Chanock, S, Gaziano, J, Giovannucci, E, Hallmans, G
Format: Journal article
Language:English
Published: 2010