Some p53-binding proteins that can function as arbiters of life and death.
Four sets of p53-binding proteins are discussed in this review. These are the E2F family, the ASPP family, Y-box-binding protein YB1, and the prolyl isomerase Pin1. Each appears to play a role in the decision by p53 to induce an arrest of cell proliferation or apoptosis and they may also be independ...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2006
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