The C-terminal helix of BubR1 is essential for CENP-E-dependent chromosome alignment

During cell division, misaligned chromosomes are captured and aligned by motors before their segregation. The CENP-E motor is recruited to polar unattached kinetochores, to facilitate chromosome alignment. The spindle checkpoint protein BubR1 has been reported as a CENP-E interacting partner, but to...

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Bibliographic Details
Main Authors: Legal, T, Hayward, D, Gluszek-Kustusz, A, Blackburn, EA, Spanos, C, Rappsilber, J, Gruneberg, U, Welburn, JPI
Format: Journal article
Language:English
Published: The Company of Biologists 2020