Amplicon-based detection and sequencing of SARS-CoV-2 in nasopharyngeal swabs from patients with covid-19 and identification of deletions in the viral genome that encode proteins involved in interferon antagonism

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19). Sequencing the viral genome as the outbreak progresses is important, particularly in the identification of emerging isolates with different pathogenic potential and to identify...

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Main Authors:	Moore, SC, Penrice-Randal, R, Alruwaili, M, Randle, N, Armstrong, S, Hartley, C, Haldenby, S, Dong, X, Alrezaihi, A, Almsaud, M, Bentley, E, Clark, J, García-Dorival, I, Gilmore, P, Han, X, Jones, B, Luu, L, Sharma, P, Shawli, G, Sun, Y, Zhao, Q, Pullan, ST, Carter, DP, Bewley, K, Dunning, J, Zhou, E-M, Solomon, T, Beadsworth, M, Cruise, J, Crook, DW, Matthews, DA, Davidson, AD, Mahmood, Z, Aljabr, W, Druce, J, Vipond, R, Ng, L, Renia, L, Openshaw, PJM, Baillie, JK, Carroll, MW, Stewart, J, Darby, A, Semple, M, Turtle, L, Hiscox, JA
Format:	Journal article
Language:	English
Published:	MDPI 2020

Amplicon-based detection and sequencing of SARS-CoV-2 in nasopharyngeal swabs from patients with covid-19 and identification of deletions in the viral genome that encode proteins involved in interferon antagonism

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