Immune checkpoint modulation enhances HIV-1 antibody induction
Eliciting protective titers of HIV-1 broadly neutralizing antibodies (bnAbs) is a goal of HIV-1 vaccine development, but current vaccine strategies have yet to induce bnAbs in humans. Many bnAbs isolated from HIV-1-infected individuals are encoded by immunoglobulin gene rearrangments with infrequent...
Main Authors: | , , , , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
Springer Nature
2020
|